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Mobile responses are tissue and context dependent in terms of each biochemical and biomechanical cues ( Bissell and Radiskyhttp://www.landschaftsgaertener.com 2001 ; Yu et al.http://www.landschaftsgaertener.com 2010 ). Hencehttp://www.landschaftsgaertener.com understanding the complicated processes surrounding ECM productionhttp://www.landschaftsgaertener.com modification and remodelinghttp://www.landschaftsgaertener.com and relating these processes to physiological adjustments within the biochemical and biomechanical properties of the ECMhttp://www.landschaftsgaertener.com are key to determining how microenvironmental adjustments influence cellular responses.
In micehttp://www.landschaftsgaertener.com C-X-C chemokine receptor 4 (CXCR4) and C-C chemokine receptors 2 and 7 (CCR2 and CCR7) have been proven to mediate lung healing and fibrosis by recruiting these fibrocytes ( Phillips et al.http://www.landschaftsgaertener.com 2004 ; Moore et al.http://www.landschaftsgaertener.com 2005 ; Strieter et al.http://www.landschaftsgaertener.com 2007 …
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